Cerebral amyloid angiopathy-CT

Cerebral amyloid angiopathy (CAA) refers to the deposition of b -amyloid in the media and adventitia of small- and mid-sized arteries (and less frequently, veins) of the cerebral cortex and the leptomeninges. It is a component of any disorder in which amyloid is deposited in the brain, and it is not associated with systemic amyloidosis. CAA has been recognized as one of the morphologic hallmarks of Alzheimer disease (AD), but it is also often found in the brains of elderly patients who are neurologically healthy. While often asymptomatic, CAA may lead to dementia, intracranial hemorrhage (ICH), or transient neurologic events. ICH is the most recognized result of CAA.
This is a case of 68yr old man with old history of right frontal bleed presented with fresh bleed in the same area for which he was operated. Following he developed a left frontal heamtoma. Reoperated on the other side. Following which he had a left parietal hematoma. Diagnosis of CAA was kept and was confirmed histopathologically by congo red staining. Serial CT scans are provided.

Dr.Sumer K Sethi, MD
Sr Consultant Radiologist ,VIMHANS and CEO-Teleradiology Providers
Editor-in-chief, The Internet Journal of Radiology
Director, DAMS (Delhi Academy of Medical Sciences)