ANKYLOSING SPONDYLITIS-MRI
There is a spectrum of destructive lesions involving the discovertebral junction in ankylosing spondylitis known as Anderson’s lesion. It may be of 2 types -
1. An "inflammatory" type characterized by a defect in one or two neighbouring vertebral bodies surrounded by reactive sclerosis and associated with varying degrees of disc space narrowing.
2. A "non-inflammatory" type showing predominantly osteolytic destruction with little disc space narrowing and sclerosis.
The MRI characteristics of the disc also help to distinguish the Anderson lesion from infection spondylitis. In most cases the major part of the disc shows decreased signal intensity on T2 weighted images (due to fibrous replacement of the disc), while generalized increased signal intensity due to inflammatory oedema and granulation tissue would be expected in established acute infective spondylitis
Erosions on the antero-lateral margins of the vertebrae with sclerosis associated with enthesitis are known as Romanus sign or Shiny corner sign.
Focal areas of increased signal intensity in disc correspond to active inflammatory granulation tissue.
Bone marrow fat deposits can be seen as hyperintense areas in vertebrae on both T1 and T2 sagittal images.
In severe cases, ankylosis followed by kyphosis noted.
Paravertebral soft tissue masses are uncommon as seen in infective diskitis.
1. An "inflammatory" type characterized by a defect in one or two neighbouring vertebral bodies surrounded by reactive sclerosis and associated with varying degrees of disc space narrowing.
2. A "non-inflammatory" type showing predominantly osteolytic destruction with little disc space narrowing and sclerosis.
The MRI characteristics of the disc also help to distinguish the Anderson lesion from infection spondylitis. In most cases the major part of the disc shows decreased signal intensity on T2 weighted images (due to fibrous replacement of the disc), while generalized increased signal intensity due to inflammatory oedema and granulation tissue would be expected in established acute infective spondylitis
Erosions on the antero-lateral margins of the vertebrae with sclerosis associated with enthesitis are known as Romanus sign or Shiny corner sign.
Focal areas of increased signal intensity in disc correspond to active inflammatory granulation tissue.
Bone marrow fat deposits can be seen as hyperintense areas in vertebrae on both T1 and T2 sagittal images.
In severe cases, ankylosis followed by kyphosis noted.
Paravertebral soft tissue masses are uncommon as seen in infective diskitis.
ANKYLOSING SPONDYLITIS-MRI
Reviewed by Sumer Sethi
on
Friday, March 05, 2010
Rating:
Reviewed by Sumer Sethi
on
Friday, March 05, 2010
Rating:
Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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