Polycystic Kidney Disease-CT

ADPKD is the most common of all the hereditary cystic kidney diseases.  ADPKD is characterized by progressive cyst development and bilaterally enlarged kidneys with multiple cysts. Cyst formation begins in utero from any point along the nephron, although fewer than 5% of nephrons are thought to be involved. As the cysts accumulate fluid, they enlarge, separate entirely from the nephron, compress the neighboring renal parenchyma, and progressively compromise renal function. The major extrarenal complications of ADPKD include cerebral aneurysms, hepatic cysts, pancreatic cysts, cardiac valve disease, colonic diverticula, and aortic root dilatation. These are CT images of 46 year old male showing enlarged kidneys with multiple cysts and renal calculus along with associated hepatic cysts.