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Osteopoikilosis- "Spotted Bone Disease"


Imaging Findings
Well-defined sclerotic lesions clustered symmetrically around joints
The long axis of the lesion is typically lined-up with the long axis of the bone
Bone islands may have a thorny appearance
Low signal intensity on T1 and T2 weighted MRI images
Bone scan is normal

Case submitted by Dr MGK Murthy & Hari Om


Differential Diagnosis
Osteoblastic metastatic disease :Osteopoikilosis is symmetrical, periarticular and the lesions are uniform in size
Tuberous sclerosis
Mastocytosis
Osteopoikilosis- "Spotted Bone Disease" Reviewed by Sumer Sethi on Wednesday, January 18, 2012 Rating: 5

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