Grey matter heterotopia-MRI
Grey matter heterotopias are characterised by interruption of normal neuronal migration from near the ventricle to the cortex. This patient presented with refractory seizures with MRI showed nodular subependymal & subcortical heterotopia. Grey matter heterotopias can be divided macroscopically into:
nodular heterotopias
- subependymal heterotopia : most common
- subcortical heterotopia
diffuse heterotopias
- band heterotopia
- lissencephaly
- laminar heterotopia
Grey matter heterotopia-MRI
Reviewed by Sumer Sethi
on
Friday, December 14, 2012
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Heterotopias are part of a spectrum of disorders known as "neuronal migration defects" . All are single gene disorders and for many genetic testing is available in India. Appropriate molecular testing can help in providing recurrence risk (which may be upto 25%)and prenatal diagnosis. Such patients need evaluation by geneticists.
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