Multisystem Atrophy versus Parkinsonism-MRI- Teaching Points
What your Neurologist wants to know?
Brain MRI in patients with MSA-P and MSA-C may reveal atrophy of the putamen, pons, and middle cerebellar peduncles. On T2 MRI sequences, signal changes include hypointensity of the posterior putamen (also described as a slit-like void), a hyperintense lateral putaminal rim, and hyperintensities of the middle cerebellar peduncles. These changes are supportive of the diagnosis of MSA rather than idiopathic Parkinson disease. The "hot cross bun sign" refers to hyperintense T2 signal in the shape of a cross within the pons that arises from degeneration of transverse pontocerebellar fibers.
Multisystem Atrophy versus Parkinsonism-MRI- Teaching Points
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Reviewed by Sumer Sethi
on
Thursday, April 04, 2013
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Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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