Radium 223-Update
NEJM (N Engl J Med 2013; 369:276-278) latest issue, Vapiwala et al report : Radium-223 dichloride (radium-223), an alpha emitter, selectively targets bone metastases with alpha particles in men with castration-resistant prostate cancer and bone metastases. Radium-223 dichloride (radium-223), the first alpha emitter to undergo phase 3 testing and receive approval for clinical use, acts independently of cell cycles, surface markers, and tumor types. The simplicity of the alpha emitter radium-223 lies in its winning combination of a convenient half-life (11.4 days) and its inherent bone-seeking and potent DNA-damaging properties.
Radium 223-Update
Reviewed by Sumer Sethi
on
Friday, July 19, 2013
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