Blood brain barrier in Radiology
- Why do brain pathologies enhance on Gd MRI: Contrast will not leak into the brain until the Blood brain barrier is damaged. Enhancement is seen when a CNS tumor destroys the BBB.
- Extra-axial tumors such as meningiomas and schwannomas are not derived from brain cells and do not have a blood-brain barrier. Therefore they will enhance.
- In gliomas - like astrocytomas, oligodendrogliomas and glioblastoma multiforme - enhancement usually indicates a higher degree of malignancy.
- Gangliogliomas and pilocytic astrocytomas are the exceptions to this rule: they are low-grade tumors, but they enhance vividly.
Blood brain barrier in Radiology
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Reviewed by Sumer Sethi
on
Monday, May 12, 2014
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Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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