'Swallow Tail' appearance and Parkinsonism-Role of 7Tesla MRI
- There is no well-established in vivo marker of nigral degeneration in Parkinson's disease (PD).
- High-resolution, iron-sensitive, magnetic resonance imaging (MRI) at 7T allows direct nigrosome-1 visualisation in healthy people but not in PD.
- Nigrosome-1 is located in the posterior third of the substantia nigra, returns a high signal on SWI in a ‘linear’, ‘comma’ or ‘wedge’ shape and is surrounded by low SWI signal intensity anterior and laterally (pars compacta SN) and medially by low signal from the medial leminiscus.
- Nigrosome-1 and its surrounding structures have resemblance to the tail of a swallow on axial imaging HR-SWI
Reference and further reading :
- Schwarz ST, Afzal M, Morgan PS, Bajaj N, Gowland PA, et al. (2014) The ‘Swallow Tail’ Appearance of the Healthy Nigrosome – A New Accurate Test of Parkinson's Disease: A Case-Control and Retrospective Cross-Sectional MRI Study at 3T. PLoS ONE 9(4): e93814. doi:10.1371/journal.pone.0093814
'Swallow Tail' appearance and Parkinsonism-Role of 7Tesla MRI
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Reviewed by Sumer Sethi
on
Thursday, September 04, 2014
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Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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