Radiology helps in understanding Alzheimer's disease
Researchers at Keck Medicine of USC used high-resolution imaging of the living human brain to show for the first time that the brain's protective blood barrier becomes leaky with age, starting at the hippocampus.
Key Point about the study: High-resolution MRI analysis of regional BBB permeability in the living human brain. BBB breakdown during normal aging begins in the hippocampus. Accelerated BBB breakdown in the hippocampus may contribute to cognitive impairment.
Article cited:
Montagne, A., Barnes, S. R., Sweeney, M. D., Halliday, M. R., Sagare, A. P., Zhao, Zlokovic, B. V. (2015). Blood-brain barrier breakdown in the aging human hippocampus. Neuron, 85, 1-7. Published online Jan. 21, 2015; doi:10.1016/j.neuron.2014.12.032
Radiology helps in understanding Alzheimer's disease
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Reviewed by Sumer Sethi
on
Friday, January 23, 2015
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Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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