Iodinated Contrast Agents Amplify DNA Radiation Damage-Journal Reports
According to original research by Eike I. Piechowiak, MD et al, published ahead of print in Radiology, points out that iodinated contrast amplify DNA damage with radiation. This needs further confirmations and studies to assess the significance of this finding.
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As per the researchers Blood samples were taken from the patients prior to and immediately after CT. In these blood samples, the average number of phosphorylated histone H2AX (γH2AX) foci per lymphocyte was determined with fluorescence microscopy. Article concluded, " the application of iodinated contrast agents during diagnostic x-ray procedures, such as chest CT, leads to a clear increase in the level of radiation-induced DNA damage as assessed with γH2AX foci formation."
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Further Reading: http://pubs.rsna.org/doi/abs/10.1148/radiol.14132478
Iodinated Contrast Agents Amplify DNA Radiation Damage-Journal Reports
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Reviewed by Sumer Sethi
on
Thursday, February 12, 2015
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Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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