Antibody positive autoimmune encephalitis presenting with faciobrachial dystonic seizures-Case Report
63 year old male presented with new onset faciobrachial dystonic seizures. Imaging showed T2 Flair hyperintensity in left hippocampus. Possibility of autoimmune encephalitis was considered and we went for CSF autoantibody study.Result came as positive for LGI 1 (Leucine rich Glioma Inactivated-1) antibody in CSF.
We also did a paraneoplastic work up to rule out any underlying malignancy. But was unyielding. Patient was treated with steroid pulse with methylprednisolone for 5 days. Subsequently, he was continued on oral steroids. Patient improved. No further seizure episodes. Patient is being kept on follow up.
Final diagnosis
Faciobrachial dystonic seizures
Autoimmune limbic encephalitis
LGI 1 antibody positive
Case Submitted by
Dr Rahul Rajeev, DM Neurology (Std)
Antibody positive autoimmune encephalitis presenting with faciobrachial dystonic seizures-Case Report
Reviewed by Sumer Sethi
on
Sunday, December 09, 2018
Rating:
Reviewed by Sumer Sethi
on
Sunday, December 09, 2018
Rating:
Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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