Methanol Poisoning : MRI
Clinical Features
21 year old : accidentally had methanol ingestion, developed visual complete visual loss and high anion gap metabolic acidosis.
Mechanism of Action
Methanol ----- metabolized into formaldehyde----- formate------ highly toxic respiratory chain metabolism toxin---- inhibits cytochrome oxidase
MRI findings
Methanol poisoning characteristically tends to bilaterally affect the putamen, optic nerves, and retina, but can also affect other basal ganglia nuclei, subcortical white matter, and cerebellum. In this patient because MRI was done in acute setting revealed hyperintense signal on DW-MRI for diffusion restriction.
21 year old : accidentally had methanol ingestion, developed visual complete visual loss and high anion gap metabolic acidosis.
Mechanism of Action
Methanol ----- metabolized into formaldehyde----- formate------ highly toxic respiratory chain metabolism toxin---- inhibits cytochrome oxidase
MRI findings
Methanol poisoning characteristically tends to bilaterally affect the putamen, optic nerves, and retina, but can also affect other basal ganglia nuclei, subcortical white matter, and cerebellum. In this patient because MRI was done in acute setting revealed hyperintense signal on DW-MRI for diffusion restriction.
Methanol Poisoning : MRI
Reviewed by Sumer Sethi
on
Monday, April 20, 2020
Rating:
Reviewed by Sumer Sethi
on
Monday, April 20, 2020
Rating:
Sumer Sethi
Unique blend of academic excellence and entrepreneurship, heading leading firms in India- Teleradiology Providers, pioneering company providing teleradiology services and DAMS (Delhi Academy of Medical Sciences) Premier test preparation institute in India for MD/MS/MCI preparation. He has also been an invited faculty member at various conferences, including Teleradiology in IRIA 2008 and 2011, Hospital Build Middle East, Congress of the Brain Tumor Radiology in Neuro-oncology Society. Dr. Sethi is Editor-in-Chief of Internet Journal of Radiology. He has a keen interest in Web 2.0 technologies and in maintaining his famous radiology blog, which has been featured in multiple international journals.
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